Lieberkühn

 









Paneth cells are found in the crypts of Lieberkühn in the small intestine. They are specialized epithelial cells that produce granules containing: Antimicrobial peptides, Immunomodulating proteins, Lysozyme, Phospholipase A2.


enterocytes in the crypts of Lieberkühn are responsible for secreting intestinal fluid. 

Enterocytes are also known as intestinal absorptive cells. They are columnar epithelial cells that line the inner surface of the small and large intestines. 

Enterocytes have the following characteristics: 

Glycocalyx surface coat: Contains digestive enzymes

Microvilli: Increase surface area, which facilitates the transport of small molecules

Endocrine role: Secrete hormones such as leptin


goblet cells are mucus-secreting cells found in the large intestine. They are also known as crypts of Lieberkühn. 

Goblet cells are unicellular glands that are scattered in the mucous membranes of the small and large intestine. 

 They secrete mucins, which are large glycoproteins that protect mucous membranes. 

 Mucins also trap microorganisms and protect tissue from chemical damage.



chief cells are epithelial cells in the stomach that secrete pepsinogen. 

 Pepsinogen is an inactive proenzyme form of pepsin. 

 The acidic environment of the stomach activates pepsinogen by cleaving the blocking amino acid sequence. 

 The active pepsin protease can then digest proteins in the chyme. 



chief cells are located in the bottom of the crypts of Lieberkuhn.